GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs4660306 | 1 | rs11211132 | chr1:45990516 | CCDC163P | chr1:45960581-45965646:- | -0.76 | -7.95 | 1.07E-10 | Homocysteine levels |
| UVM | cis | rs2564921 | 1 | rs11242 | chr3:53125922 | RFT1 | chr3:53122503-53164470:- | 0.34 | 4.6 | 2.54E-5 | Height |
| UVM | cis | rs11190604 | 1 | rs11292 | chr10:102313607 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs78153629 | 1 | rs113638727 | chr15:40706101 | C15orf23 | chr15:40674922-40686488:+ | 0.87 | 4.85 | 1.04E-5 | Heschl's gyrus morphology |
| UVM | cis | rs10935120 | 1 | rs1138273 | chr3:134261437 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 6.87 | 6.1E-9 | Height |
| UVM | cis | rs78153629 | 1 | rs11557072 | chr15:40713374 | C15orf23 | chr15:40674922-40686488:+ | 0.91 | 5.13 | 3.95E-6 | Heschl's gyrus morphology |
| UVM | cis | rs2239557 | 1 | rs11628710 | chr14:74649280 | LIN52 | chr14:74551656-74667117:+ | 0.44 | 5.65 | 5.92E-7 | Common traits (Other) |
| UVM | cis | rs6500602 | 1 | rs11647946 | chr16:4462836 | HMOX2 | chr16:4524719-4560347:+ | 0.46 | 4.72 | 1.68E-5 | Schizophrenia |
| UVM | cis | rs1167827 | 1 | rs1167827 | chr7:75163169 | PMS2L3 | chr7:75137070-75157418:- | -0.65 | -6.2 | 7.74E-8 | Body mass index |
| UVM | cis | rs13008299 | 1 | rs11689927 | chr2:29248604 | FAM179A | chr2:29204164-29275094:+ | -0.68 | -5.37 | 1.64E-6 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs13008299 | 1 | rs11691201 | chr2:29248816 | FAM179A | chr2:29204164-29275094:+ | 0.72 | 5.51 | 9.95E-7 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs8135828 | 1 | rs11704899 | chr22:29918482 | CABP7 | chr22:30116344-30127818:+ | 0.97 | 5.98 | 1.73E-7 | Lipid traits |
| UVM | cis | rs10935120 | 1 | rs11706117 | chr3:134212526 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs11708531 | chr3:134224902 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |
| UVM | cis | rs9876781 | 1 | rs11712561 | chr3:48435272 | TREX1 | chr3:48501186-48509043:+ | -0.38 | -4.8 | 1.25E-5 | Longevity |